The aim of this study was to develop a simple and rapid tablet suspension method using a microwave oven. Cortril® tablets (uncoated tablet), Cravit® tablets (coated tablet), and Dantrium® capsules (capsule) were used as the test reagents. The three drugs were suspended by simply using a microwave oven set at 500 W for 10 seconds followed by about one minute of shaking. The analysis of the suspensions by high-performance liquid chromatography with photodiode-array detection confirmed that no new compounds or decomposition products were produced by the treatment with the microwave oven. In addition, quantitative analysis of the main ingredient of each drug was almost 100%. The suspension method using a microwave oven is very simple and rapid. And the microwave oven suspension method is expected to become a new administering drugs method for swallowing difficulties patients.