Krishna Teja Pharmacy College, Chadalawada Nagar, Tirupathi - 517506, Andhra Pradesh, India

Krishna Teja Pharmacy College, Chadalawada Nagar, Tirupathi - 517506, Andhra Pradesh, India

Krishna Teja Pharmacy College, Chadalawada Nagar, Tirupathi - 517506, Andhra Pradesh, India
UV Spectroscopy ,Q - absorption ratio method , beclomethasone dipropionate ,Clotrimazole ,

A simple UV spectroscopic method was developed and validated for the estimation of Beclomethazone dipropionate and Clotrimazole in bulk and pharmaceutical dosage form using methanol and buffer as solvent. The quantification was achieved at 240nm. Beers law was obeyed in the concentration range of 10-100 μg/ml for Clotrimazole and 2.5-25 μg/ml for Beclomethasone. The results of analysis have been validated statistically. The relative standard deviation was found to be less than 2.0%. The assay result of marketed formulation was calculated. The present result shows that the proposed method can be successfully implemented for the estimation of Beclomethasone dipropionate and Clotrimazole in bulk and its marketed formulations.

4 , 7 , 2014