ISSN

2277 - 3282

e ISSN

2277 - 3290

Publisher

Journal of Science

THYROID DISORDERS AND NITRIC OXIDE LEVELS
Author / Afflication
Monica Verma

Senior Resident, Department of Biochemistry, Pt. B.D. Sharma University of Health Sciences, Rohtak, Haryana- India.
Kiran Dahiya

Professor, Department of Biochemistry, Pt. B.D. Sharma University of Health Sciences, Rohtak, Haryana- India
Veena Singh Ghalaut

Senior Professor and Head, Department of Biochemistry, Pt. B.D. Sharma University of Health Sciences, Rohtak, Haryana- India
Shashi Seth

Senior Professor, Department of Biochemistry, Pt. B.D. Sharma University of Health Sciences, Rohtak, Haryana- India.
Prasanta Saha Roy

Biochemist, Department of Biochemistry, Pt. B.D. Sharma University of Health Sciences, Rohtak, Haryana- India.
Atreyee Basu

Ex Resident, Department of Biochemistry, Pt. B.D. Sharma University of Health Sciences, Rohtak, Haryana- India
Abhishek Soni

Senior Resident, Department of Radiotherapy, Pt. B.D. Sharma University of Health Sciences, Rohtak, Haryana- India.
Keywords
Hyperthyroidism ,HypothyroidismNitric oxide ,Nitric oxide ,Total triiodothyronine ,Total thyroxine ,Thyroid stimulating hormone ,
Abstract

Nitric oxide has been regarded as a marker of oxidative stress in various diseases. There is a lot of controversy regarding levels of nitric oxide in thyroid disorders. The present study included 50 diagnosed hypothyroid, 50 hyperthyroid and 50 healthy controls. The nitric oxide levels were estimated by Griess reaction. The results were compared statistically. Nitric oxide concentration was found to be significantly low in hyperthyroid patients (6.4±3.8 µmol/L) as compared to control subjects (36.24±7.61 µmol/L) (p < 0.05), while it was significantly raised in hypothyroid patients (57.6±15.8 µmol/L) (p < 0.001). Estimation of nitric oxide levels in thyroid disorders may aid in understanding the etiopathogenesis of thyroid disorders.

Volume / Issue / Year

5 , 1 , 2015

Starting Page No / Endling Page No

4 - 8