Department of Anesthesiology, SRMS IMS, Bareilly, India.

Head, Department of Anesthesia, SRMS IMS, Bareilly, India.
IOP ,Anaesthetic ,Intra ocular Pressure ,Laparoscopic Surgery ,

Aims to study the changes in IOP by nitrous oxide during general surgery and by CO2 and N20 in laparoscopic surgery in trendelenberg and antitrendelenberg position. Study comprised of two groups-Group A (general surgery), Group B (Laparoscopic surgery) each having 50 cases. Group B further subdivided into B1(antitrendelenberg position) and B2 (trendelenberg position). In group A , IOP was measured preop;15, 30, 45 minutes intraop and post op .In group B IOP was measured preoperatively , after CO2 insufflation , in head up / head down position, mid - surgery and post operatively. In group A, Preop. IOP(Mean±S.D) was 16.1± 2.3 mmHg; IOP at 15, 30, 45 min. intraop was 12.6±2.2, 14.0±2.6 and 14.5±2.6 respectively. Post op. IOP was 15.7±2.2 mmHg. In group B, Preop. IOP was 15.8±1.9. IOP after CO2 insufflation, mid of surgery and post op was 17.5±1.9, 16.4±1.9, 16.7±2.1 respectively. IOP in head up position in group B1 and head down position in group B2 was 14.2±2.3 and 18.9±1.9 respectively. IOP decreases during general surgery after nitrous oxide and isoflurane administration. Although there is significant difference in IOP during preoperative and intraoperative phase, IOP steadily increases towards baseline as the surgery progresses and in post-operative period, it nearly comes to baseline. In group B, CO2 insufflation causes significant increase in IOP. During surgery, head up or head down position causes significant decrease or increase in IOP respectively. There is a significant difference in IOP in preoperative phase, during CO2 insufflation, head up/head down position. IOP nearly comes to baseline at the end of surgery. There is no significant difference in IOP in pre and postoperative stage in both group A and B. IOP do not cross the normal range in both group of patients at any time of surgery.

5 , 6 , 2015