ISSN

2277 - 3282

e ISSN

2277 - 3290

Publisher

Journal of Science

SYNTHESIS, CYTOTOXICAND PRO-APOPTOTIC ACTIVITY OF CERTAIN PYRAZOLOPYRIMIDINE DERIVATIVES
Author / Afflication
Noura Sayed

Pharmaceutical Chemistry Department, Faculty of Pharmacy, Heliopolis University for Sustainable Development, Egypt.
Rabah Ahmed Taha

Pharmaceutical Chemistry Department, Faculty of Pharmacy, Ain Shams University, Egypt.
Mohamed Kamal Abdel Hamid

Pharmaceutical Chemistry Department, Faculty of Pharmacy, Cairo University, Egypt.
DalaA.AbouEla

Pharmaceutical Chemistry Department, Faculty of Pharmacy, Ain Shams University, Egypt.
Keywords
Pyrazolopyrimidines ,Anticancer ,Synthesis ,
Abstract

Pyrazolopyrimidines are the fused heterocyclic ring systems which structurally resemble purines which prompted biological investigations to assess their potential therapeutic significance. They are known to play a crucial role in numerous disease conditions especially cancer. The advent of their first bioactivity as adenosine antagonistic property divulged their medicinal potential. The collective anticancer results were described.

Volume / Issue / Year

6 , 7 , 2016

Starting Page No / Endling Page No

370 - 379