The alarming spread of infectious diseases had led researchers to look for newer approaches of oral health restoration. Despite over 50 years of antibiotics use, oral infectious diseases remain a major health problem, with fewer declines in infection rates & emergence of multiple drug resistant bacteria‘s. The probiotics concept essentially entails the introduction of specific viable microbial species in order to confer health benefits upon a host by functioning via different mechanisms. The modulation of the microbiota for restoring and maintaining health have led to development of Probiotic which are bacteria‘s with beneficial effects for humans and animals. Several clinical studies have proven their beneficial effects in various oral diseases including halitosis, gingivitis, periodontitis, dental caries & oral candidiasis.