One of the most common causes of pain in anal region is the Fissure-in-ano. It presents as longitudinal/linear tear of the anal squamous epithelial lining to the dentate line of the anus. It is usually seen in the anoderm or the distal end of the anal canal. Due to poor perfusion nature of the anal wall and unsupported nature, the tear of fissure usually extends from dentate line to verge of the anal canal. Anal fissure can be assumed as never fatal condition but it highly shows its impact on quality of life of individual by its symptoms like pain, constipation, and bleeding per rectum. The pain is assessed to be severe in patients with fissure especially during defecation and this results in delaying defecation by the individual to avoid pain. Materials required for the study was collected form the respective departments of the hospital. Most of the study material was collected from the medical records room of the individual hospital department. Complete study was processed under supervision of the higher health care professionals. 44 patients presented with overweight or obese condition, 34 were of normal weight, about 4 patients were under the age group of <15 years, about 43 fell in between the age group of 15-40 years, and more than 40 years included about 31 patients. Thus, in the study it has been observed that, pain and bleeding is the major symptom of fissure-in-ano. Overweight/ obesity is the major riskfactor with associated constipation. Decreased physical activity might be an another reason and males are more prone to fissure-in-ano, in comparison with females.