Abstract
COMPARATIVE STUDY OF EFFICACY OF GABAPENTIN AND TRAZODONE IN CHRONIC ALCOHOLICS FOR INSOMNIA

Studies of the efficacy of gabapentin and tranzodone for treating alcohol use disorder (AUD) have yielded mixed findings. Alcohol-dependent outpatients with persisting were treated with either gabapentin or trazodone. Patients were assessed at baseline and after 24 weeks on medication using the Ham-D Scaling Factors. Of 60 cases initially treated, 10% dropped out due to morning drowsiness. Of the remaining 54 cases, 35 were treated with gabapentin (mean dose ± SD = 888 ± 900 mg) at bedtime and 19 were treated with trazodone (105 ± 50 mg) at bedtime. Both groups improved significantly on the Ham-D, however, the gabapentin group improved significantly more than the trazodone group. Controlled studies are warranted to replicate these findings.