ISSN
2277 - 3282
e ISSN
2277 - 3290
Publisher
Journal of Science
VISIBLE SPECTROPHOTOMETRIC DETERMINATION OF ENTECAVIR IN PHARMACEUTICAL DOSAGE FORMS
Author / Afflication
Reddy Rambabu
Chebrolu Hanumaiah Institute of Pharmaceutical Sciences, Guntur, Andhra Pradesh, India.
Jampani Subbarao
Chebrolu Hanumaiah Institute of Pharmaceutical Sciences, Guntur, Andhra Pradesh, India.
S Vidyadhara
Chebrolu Hanumaiah Institute of Pharmaceutical Sciences, Guntur, Andhra Pradesh, India.
Battula Sowjanya Lakshmi
Chebrolu Hanumaiah Institute of Pharmaceutical Sciences, Guntur, Andhra Pradesh, India.
Keywords
Simple ,Spectrophotometer ,Maximum ,Entecavir ,Beers-law ,Concentration ,
Abstract
A simple and sensitive method was developed for the determination of Entecavir by visible spectrophotometry using chromogenic reagent, N-(1-naphthyl ethylene diamine). Entecavir forms a red coloured complex with the reagent which shows maximum absorption at 549nm and obeys beer-lamberts law in the concentration range of 25-Simple125μg/ml. The correlation coefficient was calculated 0.9982.
Volume / Issue / Year
4 , 10 , 2014
Starting Page No / Endling Page No
600 - 603