Department of Anaesthesiology, Mallareddy Institute of Medical Sciences, Quthabullapur, Hyderabad, Telangana, India.

Department of Anaesthesiology, Mallareddy Institute of Medical Sciences, Quthabullapur, Hyderabad, Telangana, India.
Lidocain ,Cortisol ,Amylase ,Calcium ,Oxidative stress ,

In this study we have investigated the effect of Lidocain a local anaesthetic drug on salivary cortisol, salivary alphaamylase levels and calcium (salivary biomarkers) in selected subjects undergoing extraction of wisdom tooth. During experimentation, total two saliva samples were gathered: one 1 hour prior to dental procedure, second one 1 hour later to procedure. We have observed increased in cortisol, amylase and calcium levels after the procedure compared to normal. The significant increase in these salivary components may be due to the oxidative stress induced by the Lidocain during the local anaesthesia. These salivary biomarkers may be a valuable tool for evaluating oxidative stress and psychological stress while performing the dental procedures.

5 , 6 , 2015