Department of Medical Parasitology, Faculty of Medical Laboratory Sciences, Al Neelain University, Khartoum, Sudan.

Department of Medical Parasitology, Faculty of Medical Laboratory Sciences, Al Neelain University, Khartoum, Sudan.

Department of Medical Parasitology, Faculty of Medical Laboratory Sciences, Al Neelain University, Khartoum, Sudan.
Toxoplasmao gondii antibodies rate ,ELISA ,

This was a cross sectional hospital based study to determine Toxoplasmao gondii antibodies rate (IgM, IgG) on renal transplant recipients in Sudan, which was conducted from June to the July 2012. A total of 84 serum samples were obtained from renal transplant recipients referred from different areas all over the country to the Sudanese kidney transplanted association hospital in Khartoum-Bahry. Patient’s information was recorded in a questionnaire before sampling. Approximately 5 ml of venous blood were collected from each Participant and IgG and IgM antibody against Toxoplasma was assessed by Enzyme Linked Immunosorbent Assay (ELISA) on serum samples. Overall seropositivity rate of toxoplasmosis in renal transplant recipients was found to be 40.5% (34/84). The seropositivity rate increased steadily with age. Also It was found that Eight (38.1%) of the 21 subjects had undergone kidney transplantation less than one year ago, and twenty six (41.3%) out of 63 cases have had transplantation year or more than one year ago. The overall seropositivity in males 24/58 (41.4%), was higher than in females 10/26 (38.5%). Based on the findings obtained, this preliminary study shows a relatively high prevalence of latent toxoplasmosis in renal transplant recipients. Risk factors may have significantly contributed to Toxoplasma acquisition in these patients. However, the regular surveillance through serological screening of Toxoplasma antibody in kidney transplant recipients is advisable.

5 , 8 , 2015