ISSN
2277 - 3282
e ISSN
2277 - 3290
Publisher
Journal of Science
SYNTHESIS, CYTOTOXICAND PRO-APOPTOTIC ACTIVITY OF CERTAIN PYRAZOLOPYRIMIDINE DERIVATIVES
Author / Afflication
Noura Sayed
Pharmaceutical Chemistry Department, Faculty of Pharmacy, Heliopolis University for Sustainable Development, Egypt.
Rabah Ahmed Taha
Pharmaceutical Chemistry Department, Faculty of Pharmacy, Ain Shams University, Egypt.
Mohamed Kamal Abdel Hamid
Pharmaceutical Chemistry Department, Faculty of Pharmacy, Cairo University, Egypt.
DalaA.AbouEla
Pharmaceutical Chemistry Department, Faculty of Pharmacy, Ain Shams University, Egypt.
Keywords
Pyrazolopyrimidines ,Anticancer ,Synthesis ,
Abstract
Pyrazolopyrimidines are the fused heterocyclic ring systems which structurally resemble purines which prompted biological investigations to assess their potential therapeutic significance. They are known to play a crucial role in numerous disease conditions especially cancer. The advent of their first bioactivity as adenosine antagonistic property divulged their medicinal potential. The collective anticancer results were described.
Volume / Issue / Year
6 , 7 , 2016
Starting Page No / Endling Page No
370 - 379