<?xml version="1.0" encoding="UTF-8"?><Articles><Article><id>509</id><JournalTitle>INCIDENTAL GALL BLADDER CARCINOMA EVALUATION IMPORTANCE OF ROUTINE HISTOPATHOLOGICAL EXAMINATION OF CHOLECYSTECTOMY SPECIMEN</JournalTitle><Abstract>Gall bladder carcinoma is a rare malignancy that carries a very poor prognosis. The gallbladder specimens are sent
for routine histopathological examination in the pathology department to rule out incidental gallbladder carcinoma. The
incidence of incidental gallbladder carcinoma diagnosis is estimated between 0.35 - 2 % in cholecystectomy specimens done
for benign GB diseases. This study aims to find out the incidental gallbladder carcinoma detected during routine
histopathological examination and also to access the importance of routine histopathological examination of cholecystectomy
specimens. We retrospectively reviewed the pathological laboratory and clinical details of gallbladder specimens of patients
who underwent cholecystectomy procedure for biliary diseases during three years period from October 2012 to September
2015. Total no. of cholecystectomy specimen received were 1125 out of which we observed histological evidence of
incidental gallbladder carcinoma in 22 no. of cases. Macroscopic abnormalities like thickened wall were found in all the 20
cases and in two cases polypoid mass with delicate papillary projections were observed. The frequency of incidental
gallbladder carcinoma was 1.96 % and most of the cases are detected at stage I. Due to difficulty in distinguishing
inflammatory changes of gallbladder from that of malignancy pre-operatively and in high incidence areas of GBC, routine
histopathological examination should be made mandatory in all cholecystectomy specimens.</Abstract><Email>naidingmomota@gmail.com</Email><articletype>Research</articletype><volume>6</volume><issue>8</issue><year>2016</year><keyword> Incidental Gallbladder Carcinoma,Cholecystectomy,Routine Histopathological examination</keyword><AUTHORS>Momota Naiding,Rang Nath Chaubey,Aniruddha Debnath, Sunita Singh,Anindita Paul</AUTHORS><afflication>Department of Pathology, Silchar Medical College and Hospital, Silchar, Assam, India,Department of Pathology, Silchar Medical College and Hospital, Silchar, Assam, India,Department of Pathology, Silchar Medical College and Hospital, Silchar, Assam, India,Department of Pathology, Silchar Medical College and Hospital, Silchar, Assam, India,Department of Pathology, Silchar Medical College and Hospital, Silchar, Assam, India</afflication></Article></Articles>