527A SCIENTIFIC APPROACH TO EVALUATE THE ANTICARIES EFFECT OF ALOE VERA GEL TOOTH PASTE IN EXPERIMENTAL ANIMAL MODELDisease that causes tooth decay, is known as dental caries it is infectious, and the mutans streptococci bacteria have long been identified as the primary disease-causing agents. Numerous tooth pastes and remedies are available to control the dental caries but permanent cure is still questionable. The side effects are one of most problematic issues with many modern drugs. Use of alternative therapies is common among patients with serious, chronic, or degenerative illness and to combat side effects with allopathic medicine. Herbal preparations can be derived from the root, leaves, seeds, and flowers. The preparations often contain a mixture of chemical substances may contain minerals and vitamins, and determining a specific active ingredient. Aloe vera has been used for many centuries for its curative and therapeutic properties, and although over 75 active ingredients from the inner gel have been identified. The study present study was conducted to evaluate the anti-caries activity of Aloe vera tooth paste against Streptococcus induced caries in rat teeth. The tooth paste was applied for 8 weeks and the prevention of dental caries was assessed by observing the maxilla and mandible molar teeth score. The % decrease in the caries score was found to be 50.97%, which was more than that of marketed fluoride rich tooth paste. From the result it was concluded that, Aloe veratooth paste protected the caries induced by the dental pathogen in rats.sehejan@gmail.comResearch6112016 Aloe vera,Dental Caries,Streptococcus viridansBalaji Subramaniyan R,Kayalvizhi GAssociate Professor, Department of Dentistry, Sri Lakshmi Narayana Institute of Medical Sciences, Pondicherry, India.,Professor, Department of Pediatric Surgery, Indira Gandhi Institute of Dental Science, Pondicherry, India.