721A CASE STUDY FOR MICROANGIOPATHIC COMPLICATIONS IN DIABETES MELLITUSDiabetes causes both vascular (micro and macrovascular) and non vascular complications. Microvascular complications have been divided into retinopathy, nephropathy and neuropathy. Diabetes is the main cause of adult blindness because of retinopathy, end degree renal disease because of nephropathy and foot ulcers and lower limb amputation due to neuropathy. Hyperuricemia has been associated with an accelerated chance of cardiovascular diseases and the metabolic syndrome and is extra commonplace in females. Uric acid is the quit fabricated from purine nucleotide metabolism and its excreted via the kidneys. The important source of mortality and morbidity in each type 1 and sort 2 diabetes is the hyperglycemia; which has direct and indirect effects at the human vascular tree. Hyperuricemia has been located to be associated with weight problems and insulin resistance, and therefore with kind 2 diabetes. Over latest years there was debate approximately the nature of the affiliation among raised serum uric acid awareness and cardiovascular disorder. Several research have identified that serum uric acid levels may be used as a predictor for cardiovascular events, consisting of myocardial infarction. This look at finds that Serum uric acid stages are better in sufferers with microvascular complications of kind 2 diabetes mellitus including retinopathy, neuropathy and nephropathy. Further, higher fasting blood sugar and growing age are located to be related to better uric acid ranges within the south Indian populace with type 2 diabetes mellitus. prasananthu@gmail.comResearch832018Hyperuricemia,nephropathy,type 2 diabetes,purine nucleotide metabolism, micro and MacrovascularPrashanth A BAssistant Professor, Sri Lakshmi Narayana Institute of Medical Science Medical College & Hospital, Puducherry, 605502, India